翻訳と辞書 Words near each other ・ Bryant S. Hinckley ・ Bryant Salter ・ Bryant Station, Texas ・ Bryant Stith ・ Bryant surface ・ Bryant Terry ・ Bryant Thomas Castellow ・ Bryant Town, Virginia ・ Bryant Township ・ Bryant Township, Fillmore County, Nebraska ・ Bryant Township, Graham County, Kansas ・ Bryant Township, Logan County, North Dakota ・ Bryant Tuckerman ・ Bryant Turner, Jr. ・ Bryant University ・ Bryant Villeponteau ・ Bryant W. Bailey ・ Bryant Walker ・ Bryant Washburn ・ Bryant Westbrook ・ Bryant Wright ・ Bryant Young ・ Bryant's Cove ・ Bryant's Minstrels ・ Bryant's traction ・ Bryant's triangle ・ Bryant's woodrat ・ Bryant, Alabama ・ Bryant, Arkansas ・ Bryant, California Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Bryant Villeponteau ： ウィキペディア英語版 Bryant Villeponteau Bryant Villeponteau is an American scientist, entrepreneur, and longevity expert who has worked in both academia and industry. His early work included the cloning of the RNA component of human telomerase when working at Geron Corporation, which led to his winning the 1997 Distinguished Inventor Award for cloning human telomerase along with three of his Geron teammates. In 2008, Dr. Villeponteau went on to serve as Vice President of Research of the aging genetics company Genescient, Inc., which uses machine learning technologies, biochemistry, and Drosophila genetics to develop therapeutics to help delay the aging process. He is also a cofounder of Centagen, Inc., which focuses on developing new technologies for extending human health and longevity by promoting adult stem cells. == Education and Academic Achievements == Villeponteau obtained a B.A. in Economics, a M.S. in Public Health Biostatistics, and a Ph.D. in Biology from UCLA in Los Angeles. Dr. Villeponteau was awarded a Molecular Biology Postdoctoral Fellowship in the UCLA Department of Chemistry and Biochemistry from 1978 to 1980, where he carried out genomic cloning of the B-globin gene cluster in Chickens....〔Villeponteau, B., and Martinson, H.G. (1981). Isolation and characterization of the complete chicken beta-globin gene region: frequent deletion of the adult beta-globin genes in lambda. Nucleic acids research 9, 3731-3746.〕 He continued in the same department for six more years as Assistant Research Chemist studying gene expression and chromatin structure.〔Villeponteau, B., and Martinson, H.G. (1987). Gamma rays and bleomycin nick DNA and reverse the DNase I sensitivity of beta-globin gene chromatin in vivo. Molecular and cellular biology 7, 1917-1924..〕〔Villeponteau, B., Pribyl, T.M., Grant, M.H., and Martinson, H.G. (1986). Novobiocin induces the in vivo cleavage of active gene sequences in intact cells. The Journal of biological chemistry 261, 10359-10365.〕〔Villeponteau, B., Lundell, M., and Martinson, H.G. (1984). Torsional stress promotes the DNAase I sensitivity of active genes. Cell 39, 469-478.〕〔Villeponteau, B., Landes, G.M., Pankratz, M.J., and Martinson, H.G. (1982). The chicken beta globin gene region. Delineation of transcription units and developmental regulation of interspersed DNA repeats. The Journal of biological chemistry 257, 11015-11023.〕〔Landes, G.M., Villeponteau, B., Pribyl, T.M., and Martinson, H.G. (1982). Hemoglobin switching in chickens. Is the switch initiated post-transcriptionally? The Journal of biological chemistry 257, 11008-11014.〕 His torsional stress model of chromatin involvement in gene regulation〔 was reviewed in a "Nature News and Views" article (''Nature'' 316, pp. 394–395, August 1985). From 1986 to 1992 Villeponteau was an Assistant Professor of Biochemistry at the University of Michigan Medical School with a joint appointment in the Institute of Gerontology. At Michigan, Villeponteau mostly worked on human gene regulation〔Yu, J., Bock, J.H., Slightom, J.L., and Villeponteau, B. (1994). The polyomavirus enhancer activates chromatin accessibility on integration into the HPRT gene. Molecular and cellular biology 12, 5785-5792.〕〔Irving, J., Feng, J., Wistrom, C., Pikaart, M., and Villeponteau, B. (1992). An altered repertoire of fos/jun (AP-1) at the onset of replicative senescence. Experimental cell research 202, 161-166.〕〔Feng, J., and Villeponteau, B. (1992). High-resolution analysis of c-fos chromatin accessibility using a novel DNase I-PCR assay. Biochimica et biophysica acta 1130, 253-258.〕〔Pikaart, M., Irving, J., and Villeponteau, B. (1991). Decline in histone H5 phosphorylation during erythroid senescence in chick embryos. Mechanisms of ageing and development 59, 189-195.〕〔Feng, J.L., Irving, J., and Villeponteau, B. (1991). A phosphatase inhibitor enhances the DNase I sensitivity of active chromatin. Biochemistry 30, 4747-4752.〕〔Lois, R., Freeman, L., Villeponteau, B., and Martinson, H.G. (1990). Active beta-globin gene transcription occurs in methylated, DNase I-resistant chromatin of nonerythroid chicken cells. Molecular and cellular biology 10, 16-27.〕〔Feng, J.L., and Villeponteau, B. (1990). Serum stimulation of the c-fos enhancer induces reversible changes in c-fos chromatin structure. Molecular and cellular biology 10, 1126-1133.〕〔Villeponteau, B. (1989). Immunoglobulin kappa enhancers are differentially regulated at the level of chromatin structure. Molecular immunology 44, 3407-3415.〕〔Rubtsov, M.A., Polikanov, Y.S., Bondarenko, V.A., Wang, Y.H., and Studitsky, V.M. (2006). Chromatin structure can strongly facilitate enhancer action over a distance. Proceedings of the National Academy of Sciences of the United States of America 103, 17690-17695.〕 Villeponteau also studied human cell aging using senescent human cells.〔〔〔Wistrom, C., Feng, J.L., and Villeponteau, B. (1989). Proliferative capacity of human fibroblasts when cultured in serum from young or old cows. Journal of gerontology 44, B160-163.〕〔Wistrom, C., and Villeponteau, B. (1990). Long-term growth of diploid human fibroblasts in low serum media. Experimental gerontology 25, 97-105.〕〔Wistrom, C., and Villeponteau, B. (1992). Cloning and expression of SAG: a novel marker of cellular senescence. Experimental cell research 199, 355-362.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bryant Villeponteau」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.